1. Gene expression signature of NK cells in NSG hL-7xhIL-15 humanized mice.
Gene expression signature of NK cells in NSG hL-7xhIL-15 humanized mice. RNA sequencing was performed using RNA extracted from hCD56+ splenic NK cells of conventional NSG (NSG, n = 2) and hIL-7xhIL-15 KI NSG (hIL7xhIL-15 KI NSG, n = 6) humanized mice. (A) Differentially expressing genes are shown. Gene expression profiles of human NK cells of humanized mice were compared with those from NK cells recovered from human PBMCs. (B) Expression of genes related to cytokine and cytotoxicity are shown.
Masashi Matsuda et al. LSA 2019;2:e
© 2019 Matsuda et al.