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Surgical and endovascular revision of infrainguinal vein bypass grafts: Analysis of midterm outcomes from the PREVENT III trial  Scott A. Berceli, MD,

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Presentation on theme: "Surgical and endovascular revision of infrainguinal vein bypass grafts: Analysis of midterm outcomes from the PREVENT III trial  Scott A. Berceli, MD,"— Presentation transcript:

1 Surgical and endovascular revision of infrainguinal vein bypass grafts: Analysis of midterm outcomes from the PREVENT III trial  Scott A. Berceli, MD, PhD, Nathanael D. Hevelone, MPH, Stuart R. Lipsitz, PhD, Dennis F. Bandyk, MD, Alexander W. Clowes, MD, Gregory L. Moneta, MD, Michael S. Conte, MD  Journal of Vascular Surgery  Volume 46, Issue 6, Pages e2 (December 2007) DOI: /j.jvs Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

2 Fig 1 Propensity model evaluation for freedom from subsequent graft revision or major amputation for open surgical and endovascular treatments. Analysis excludes grafts necessitating early revision for assumed technical complications and grafts revised after occlusion. Both unweighted and weighted models suggest a marginal survival benefit for grafts undergoing open surgical revision (n = 122 for open surgical cases and n = 97 for endovascular cases). Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

3 Fig 2. online only Univariate analysis of amputation and death for percutaneous and surgical interventions. There were trends toward improved survival and a reduced incidence of major amputation after percutaneous interventions; however, the event rate is small, with no significant statistical differences. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

4 Fig 3 Reinterventions after initial graft revision. An increased number of procedures are required to maintain patency after endovascular interventions (P = .009). The follow-up time in this study ranged from 0 to 396 days from initial reintervention, with means of 193 and 151 days for the open surgical and endovascular groups, respectively. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

5 Fig 4 Kaplan-Meier estimates of graft survival (ie, freedom from further revision or amputation) differentiated by index graft status at the time of the initial revision. A significant survival benefit in the open surgical group was observed in occluded grafts. Revisions in nonoccluded grafts demonstrate no statistical difference in survival after endovascular or open surgical interventions. Journal of Vascular Surgery  , e2DOI: ( /j.jvs ) Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

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