1. WT ESC incorporation does not prevent mononuclear invasion and central nucleation in WT/SGδ chimeras with less than 60% mosaicism.
WT ESC incorporation does not prevent mononuclear invasion and central nucleation in WT/SGδ chimeras with less than 60% mosaicism. Heart (A–D), diaphragm (E–H), quadriceps (I–L) and pectoralis (M–P) were paraffin sectioned and Hematoxylin and Eosin stained. WT (A,E,I,M), 60–80% WT/SGδ (B,F,J,N), 40–60% WT/SGδ (C,G,K,O) and <5% WT/SGδ (D,H,L,P) were analyzed. The dashed line separates non–phenotypic (left of line) from phenotypic (right of line) tissues. Original magnification 200× (A–D); 100× (E–P).
Joseph M. Vitale et al. J Cell Sci 2012;125:
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