1. Insulin secretion/insulin resistance (disposition) index (ΔINS/ΔGLU ÷ IR) in subjects with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes (T2DM) as a function of the 2-hour plasma glucose (PG) concentration during the OGTT (see text for a more detailed discussion). ΔINS/ΔGLU = increment in plasma insulin concentration/increment in plasma glucose concentration during oral glucose tolerance testing.
Insulin secretion/insulin resistance (disposition) index (ΔINS/ΔGLU ÷ IR) in subjects with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes (T2DM) as a function of the 2-hour plasma glucose (PG) concentration during the OGTT (see text for a more detailed discussion). ΔINS/ΔGLU = increment in plasma insulin concentration/increment in plasma glucose concentration during oral glucose tolerance testing. The curves for lean and obese individuals are shown separately. IR = insulin resistance measured with the insulin clamp technique.
Ralph A. DeFronzo et al. Diabetes Spectr 2014;27:
©2014 by American Diabetes Association