1. Supplemental Figure 1 Cell proliferation (% of mock) 20 40 60 80 10020 40 60 80
100
120
PC3
DU145 *
miR-133a (10nM)
miR-1 (10nM)
miR-Control (10nM)
mock
miR-1 (10nM) + miR-133a (10nM)
* P<0.0001

2. Supplemental Figure 4 Non-PCa PCa TAGLN2 LASS2 WDR78 P<0.0001
TAGLN2
.0002
.0004
.0006
LASS2
WDR78
P<0.0001
P=0.0030
P=0.0030
Expression levels of TAGLN2
(Normalized to GAPDH)
Expression levels of LASS2
(Normalized to GAPDH)
Expression levels of WDR78
(Normalized to GAPDH)
0.2
0.4
STXBP4
0.8
1.0
0.6
1.2
0.01
0.02
0.03
0.04
PNP
0.2
0.3
C4orf34
0.5
0.6
0.4
0.7
0.8
P=0.0097
P=0.3749
Expression levels of STXBP4
(Normalized to GAPDH)
Expression levels of PNP
(Normalized to GAPDH)
Expression levels of C4orf34
(Normalized to GAPDH)
P<0.0001
Non-PCa
PCa

3. (relative to normal tissue)
Supplemental Figure 5
(relative to normal tissue)
PNP mRNA expression
2.0
4.0
6.0
8.0
10.0
12.0
PC3
DU145
Non-PCa