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Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome  Kirsten Tillisch, Emeran A. Mayer,

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Presentation on theme: "Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome  Kirsten Tillisch, Emeran A. Mayer,"— Presentation transcript:

1 Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome  Kirsten Tillisch, Emeran A. Mayer, Jennifer S. Labus  Gastroenterology  Volume 140, Issue 1, Pages (January 2011) DOI: /j.gastro Copyright © 2011 AGA Institute Terms and Conditions

2 Figure 1 Regions showing consistent and reliable activation across all studies in healthy controls. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2011 AGA Institute Terms and Conditions

3 Figure 2 Regions showing consistent and reliable activation across all studies in patients with irritable bowel syndrome. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2011 AGA Institute Terms and Conditions

4 Figure 3 Selected axial and sagittal slices representing brain areas demonstrating difference greater activation in irritable bowel syndrome (red) and greater activation in controls (blue) across all studies. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2011 AGA Institute Terms and Conditions


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