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3 July 2019 P. 56 Complete Quick Lab p. 303 Compare and contrast:
Replication, transcription, and translation P. 57 Transcription and Translation Read pp
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The Genetic Code
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DNA and Chromosomes Chromosomes are made of DNA.
Chromosomes contain many genes. Genes code for proteins. Those proteins determine traits. The code is written as base pairs on DNA.
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Structure of DNA
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Instructions for Life DNA RNA Double strand Made by replication
Master plan Complete set of instructions Stays inside nucleus Contains thymine Sugar = deoxyribose mRNA Single strand Made by transcription Blueprints Instructions for making a single protein Carries “messages” out of nucleus into the cytoplasm to be translated into a protein. Contains uracil Sugar = ribose
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3 Types of RNA
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mRNA Messenger RNA Blueprints for building proteins out of amino acids
Take “messages” from DNA to the rest of the cell, outside the nucleus. Single strand U instead of T
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rRNA Ribosomal RNA Ribosomes use the instructions from mRNA to assemble amino acids into proteins. Ribosomes are made of proteins and rRNA.
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tRNA Transfer RNA Brings the needed amino acids to the ribosome for assembly; like a Taxi for amino acids.
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Transcription Making mRNA from DNA RNA made in nucleus
Then RNA leaves nucleus to find ribosome
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Translation Making polypeptides [proteins] from mRNA
Also called protein synthesis
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Quick Quiz What happens during: Replication Transcription Translation
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Replication Makes copies of DNA. Happens in nucleus.
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Transcription Makes mRNA from DNA. Happens in nucleus.
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Translation Makes polypeptides [proteins] from mRNA
Also called protein synthesis Happens in cytoplasm
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Proteins are made by joining amino acids into long chains called polypeptides.
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Three consecutive base pairs on a strand of mRNA are called a codon; these code for a specific amino acid.
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Before Translation Begins
A strand of mRNA must be transcribed in the nucleus and released into the cytoplasm
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Translation Begins when mRNA attaches to a ribosome
As codons move through ribosome, tRNA brings the proper amino acid to be attached to the growing polypeptide chain
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tRNA has amino acid on one end and anticodon on other
Anticodon on tRNA bonds to the codon on mRNA strand Anticodon Codon
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As tRNA brings new amino acids, the ribosome joins them together building a polypeptide
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The process continues as the ribosome moves along the mRNA strand joining new amino acids to the polypeptide until it reaches a stop codon and the polypeptide breaks away.
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IAN LHP Complete Quick Lab p. 303 Compare and contrast:
Replication, transcription, and translation
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