Download presentation
Presentation is loading. Please wait.
Published byΚασσιέπεια Σαμαράς Modified over 5 years ago
1
Model of functional coupling of LD and vacuole dynamics.
Model of functional coupling of LD and vacuole dynamics. (Left panel) TORC1-signaling from functional vacuoles (green circle) mediates mobilization of LDs during growth resumption by regulating interconversion between DAG and PA, thus allowing efficient utilization of LD (gray circle)-derived DAG for membrane lipid biosynthesis in wild-type cells. (Right panel) Defective TORC1-signaling due to dysfunctional vacuoles (red circle) prevents the efficient utilization of LD-derived DAG for PA synthesis, as well as downstream membrane lipid synthesis in, for example, ESCRT mutant (escrtΔ) cells. Sarah Ouahoud et al. J Cell Sci 2018;131:jcs213876 © Published by The Company of Biologists Ltd
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.