Download presentation
Presentation is loading. Please wait.
Published byPhilippa Klausen Modified over 5 years ago
1
Estrogenic Steroids Overall Organization of the Topic
Structure and nomenclature of natural estrogens - Estradiol, estrone, and estriol Biosynthesis and metabolism of estradiol Synthetic estrogens - Schuler’s hypothesis Estrogen antagonists - clomiphene and tamoxifen 8/5/2019 MEDC 603 Steroids
2
Estrogenic Steroids Structure and Nomenclature of Natural Estrogens
Estradioll Estrone Estriol intramuscular intramuscular oral 100% % % estr-1,3,5-triene- 3,17b-diol 3-hydroxy-estr-1,3,5 -triene-17-one estr-1,3,5-triene- 3,16a,17b-triol 8/5/2019 MEDC 603 Steroids
3
Biosynthesis and Metabolism of Estradiol
cholesterol pregnenolone testosterone estriol estrone estradiol conjugation to glucuronides, sulfates, etc…. 8/5/2019 MEDC 603 Steroids
4
Synthetic Estrogenic ethinyl-estradiol diethylstilbestrol
chlorotrianisene dienestrol 8/5/2019 MEDC 603 Steroids
5
Synthetic Estrogenic Schuler’s Hypothesis for Synthetic Estrogens
8/5/2019 MEDC 603 Steroids
6
Synthetic Estrogenic 8/5/2019 MEDC 603 Steroids
7
Estrogen Antagonists chlorotrianisene clomiphene
(estrogenic) (anti-estrogenic) tamoxifen (anti-estrogenic) 8/5/2019 MEDC 603 Steroids
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.