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MMP16 upregulation during myofibroblast differentiation
MMP16 upregulation during myofibroblast differentiation. qPCR analysis of the MKL1_S target gene MMP16 during the initial phase of hASC differentiation induced by 2 ng/ml TGF-β, 5 µM LPA, 2 µM SPC, or 5% uniaxial cyclic strain at 1 Hz for the initial 24 h. MMP16 upregulation during myofibroblast differentiation. qPCR analysis of the MKL1_S target gene MMP16 during the initial phase of hASC differentiation induced by 2 ng/ml TGF-β, 5 µM LPA, 2 µM SPC, or 5% uniaxial cyclic strain at 1 Hz for the initial 24 h. Levels are relative to GAPDH. Data are represented as mean±s.d. (n = 4). **P<0.01, ***P<0.001, n.s., not significant (unpaired Student's t-test). Matthias A. Scharenberg et al. J Cell Sci 2014;127: © Published by The Company of Biologists Ltd
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