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Expression of cGMP signaling components in polyps.
Expression of cGMP signaling components in polyps. A, Expression of cGMP generators in colon mucosa and polyps measured by real-time qPCR. B, Expression of cGMP effectors in colon mucosa and polyps assayed by real-time qPCR. C, Immunoblot analysis of cGMP effectors in colon polyps of untreated (Control) and treated (Sildenafil) mice, β-actin is a loading control. For A–B, n = 8 polyps per group, and C, n = 5 per group. *, P < 0.05; ***, P < Bianca N. Islam et al. Cancer Prev Res 2017;10: ©2017 by American Association for Cancer Research
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