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Microtubule Polymerization: One Step at a Time

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Presentation on theme: "Microtubule Polymerization: One Step at a Time"— Presentation transcript:

1 Microtubule Polymerization: One Step at a Time
David Sept  Current Biology  Volume 17, Issue 17, Pages R764-R766 (September 2007) DOI: /j.cub Copyright © 2007 Elsevier Ltd Terms and Conditions

2 Figure 1 Microtubule structures during growth and shrinkage.
Since protofilaments with GDP–tubulin prefer a curved conformation, it has been postulated that one or more terminal layers of GTP–tubulin help keep the end of the microtubule straight. Current Biology  , R764-R766DOI: ( /j.cub ) Copyright © 2007 Elsevier Ltd Terms and Conditions

3 Figure 2 The dynamic instability exhibited during microtubule growth.
Regular polymerization is interrupted by catastrophes and subsequent rescues. Current Biology  , R764-R766DOI: ( /j.cub ) Copyright © 2007 Elsevier Ltd Terms and Conditions


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