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MSCT-640 IMAGING FEATURES OF CARDIAC TUMORS IN 44 PATIENTS

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1 MSCT-640 IMAGING FEATURES OF CARDIAC TUMORS IN 44 PATIENTS
MEDIC MSCT-640 IMAGING FEATURES OF CARDIAC TUMORS IN 44 PATIENTS BS CK II. NGUYỄN XUÂN TRÌNH Department of Cardiology - MEDIC Medical Center

2 MEDIC Introduction Primary cardiac tumors are exceedingly rare, occurring in about % of autopsies. For primary cardiac tumors, about 75% are benign with myxoma accounting for at least half of reported cases and 25% are malignant. Of the malignant tumors, about 75% are sarcoma. David Kassop et al. Cardiac Masses on Cardiac CT: A Review. Curr Cardiovasc Imaging Rep (2014) 7:9281

3 MEDIC Objective Define : Characteristic imaging features of commonly encountered and selected cardiac tumors Role of cardiac CT among noninvasive imaging options.

4 MEDIC Materials and Methods A review of primary cardiac tumors of cardiac CTA referred to the Medic Medical Center between 2013 and All cardiac tumor patients were performed before and after the intravenous administration of contrast material. Imaging characteristics of cardiac tumors were confirmed by operated on for cardiac tumors and histopathological features

5 MEDIC Results There’re 44(0.0024%) cardiac tumor patients of cardiac CTA patients 24 female and 20 male, mean age years.

6 MEDIC Results Distribution of Cardiac tumors on the Basis of cardiac CTA and Surgery

7 Results Atrial Myxomas Features ( N=23) / Cardiac MSCT Location
MEDIC Results Atrial Myxomas Features ( N=23) / Cardiac MSCT Location LA (69,57%) >> RA (30,43%) Shape Spherical or ovoid (95%), ovoid with frond-like margin(4.35%), Attachment and Mobile pedunculated and mobile (60.86% ) with PPV 100%, narrow base(39,13%) Enhancement Absent to minimal , Strong ( 1 case) Attenuation and Calcification lower than myocardium(82,61%), higher than myocardium(4,35%), equal attenuation(13,04%), heterogeneous(26.08%), homogeneous(30,43%). calcification (43,47%), Margin Smooth, well-defined (78,2%), lobular contour (21,8%), Complication 1 RA myxoma was ruptured and pulmonary embolism Pericardial effusion and invasive None

8 Results Atrial Sarcomas Features ( N=6) / Cardiac MSCT Location
MEDIC Results Atrial Sarcomas Features ( N=6) / Cardiac MSCT Location RA (66,67%) >> LA (33,33%) Attachment and mobile Broad base, non mobile Enhancement Modest to intense Attenuation low attenuation, heterogeneous Margin Irregular, ill-defined, lobular contour , Invasive and Pericardial effusion Intra-/extracardiac infiltration , Bloody Pericardial effusion

9 Review of the Medical Literature
Hoffmeier A et al. Cardiac tumors—diagnosis and surgical treatment. Dtsch Arztebl Int 2014; 111(12): 205–11

10 Review of the Medical Literature
David Kassop et al. Cardiac Masses on Cardiac CT: A Review. Curr Cardiovasc Imaging Rep (2014) 7:9281

11 MEDIC LA Myxoma /Cardiac CT, 58F Case 1 Non Contrast Contrast

12 MEDIC LA Myxoma /Cardiac CT, 58F Case 1 Contrast After Contrast

13 LA Myxoma / Histopathology, 58F
MEDIC Case 1 LA Myxoma / Histopathology, 58F

14 RA Angiosarcoma / Echocardiography, 14F
MEDIC RA Angiosarcoma / Echocardiography, 14F Case 2

15 RA Angiosarcoma / Cardiac CT, 14F
MEDIC RA Angiosarcoma / Cardiac CT, 14F Case 2 Non Contrast

16 RA Angiosarcoma / Cardiac CTA, 14F
MEDIC RA Angiosarcoma / Cardiac CTA, 14F Case 2 Contrast

17 RA Angiosarcoma / Cardiac CTA, 14F
MEDIC RA Angiosarcoma / Cardiac CTA, 14F Case 2 Contrast

18 RA Angiosarcoma / Histopathology, 14F
MEDIC RA Angiosarcoma / Histopathology, 14F Case 2 Microscopic pathology photographs of primary RA Angiosarcoma. The histopathological examination with CD 34(+) and Ki67(+) immunohistochemistry confirmed the diagnosis of Angiosarcomas

19 RA Leiomyosarcoma / Cardiac CTA, 44M
MEDIC RA Leiomyosarcoma / Cardiac CTA, 44M Contrast Non Contrast Case 3 Contrast Contrast

20 RA Leiomyosarcoma /Histopathology, 44M
MEDIC RA Leiomyosarcoma /Histopathology, 44M Case 3 Microscopic pathology photographs of primary RA Leiomyosarcoma. The histopathological examination with Desmin (1+) , S100( 1+) and Vimenin (3+), EMA (-),Ki67 (15%) immunohistochemistry confirmed the diagnosis of Leiomyosarcoma

21 MEDIC Conclusion CT findings of cardiac myxomas are rarely specific, but pedunculated attachment with PPV 100%. CT findings of cardiac sarcomas were broad based attachment, multi-lobular contour, Irregular or ill-defined margin, low attenuation, moderate to intense enhancement and heterogeneous, Intra-/extracardiac infiltration, pericardial and pleural effusion, metastasis Cardiac CT is an alternative imaging modality to assess tumors

22 Thanks For Your Attention
MEDIC Thanks For Your Attention


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