1. Conceptual model of the ageing Fontan circulation
Conceptual model of the ageing Fontan circulation. a) Schematic of i) normal and ii) Fontan circulation; b) relationship between circulatory output at rest and pulmonary vascular resistance (PVR) modulated by ventricular function for a normal subject and pa...
Conceptual model of the ageing Fontan circulation. a) Schematic of i) normal and ii) Fontan circulation; b) relationship between circulatory output at rest and pulmonary vascular resistance (PVR) modulated by ventricular function for a normal subject and patients with a univentricular heart (UVH) and depressed ventricular function; c) relationship between circulatory output at rest and ventricular function modulated by PVR for a normal subject and patients with a UVH and depressed ventricular function; d) relationship between cardiac output, PVR and ventricular function during exercise for normal subjects and patients with Fontan circulation. LV: left ventricle; LA: left atrium; Ao: aorta; S: systemic circulation; RV: right ventricle; RA: right atrium; PA: pulmonary artery; P: pulmonary circulation; V: single ventricle; CV: caval veins; EF: ejection fraction. a) Reproduced from [53] with permission from the publisher.
Paul Clift, and David Celermajer Eur Respir Rev 2016;25:
©2016 by European Respiratory Society