1. Tissue oxygenation index is a useful monitor of histologic and neurologic outcome after cardiopulmonary bypass in piglets 
Ikuo Hagino, MD, Vesa Anttila, MD, David Zurakowski, PhD, Lennart F. Duebener, MD, Hart G.W. Lidov, MD, Richard A. Jonas, MD 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 130, Issue 2, Pages (August 2005)
DOI: /j.jtcvs
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

2. Figure 1
Experimental protocol depicting bypass conditions. All animals underwent the pH-stat strategy. NIRS signals were recorded every 10 seconds after induction of anesthesia and for 3 hours after weaning from CPB. Hct, Hematocrit.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

3. Figure 2
Changes in Hbo2 determined by means of NIRS. LFB, Low-flow bypass.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

4. Figure 3
Changes in TOI at 3 different low-flow rates (10, 25, 50 mL·kg−1·min−1). LFB, Low-flow bypass.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

5. Figure 4
A significant inverse correlation was identified between average TOI and NDS on the first postoperative day (Pearson r = −0.50, P = .002).
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

6. Figure 5
Significant difference in mean NDS according to TOI level. POD-1, Postoperative day 1.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions