1. TRENDS OF CANCER OBSERVED IN A PREMIER INSTITUTE IN MUMBAI, INDIA DURING LAST THREE DECADES
Dr. Ganesh B.
Prof. & Head,
Department of Medical Records, Biostatistics & Epidemiology,
Tata Memorial Hospital, Mumbai, INDIA

2. About Tata Memorial Hospital …
Tata Memorial Centre is amongst the oldest and largest cancer centres in the world, with over 75 years of exceptional patient care, high-quality training and innovative cancer research. Over the years, it has grown in size and stature, maintaining its pre-eminent position at the forefront of national and global cancer control efforts.
Compassionate patient care remains the major focus of Tata Memorial Centre, with eleven Disease Management Groups (or multidisciplinary teams) breaking departmental silos and providing optimal care for every patient. This emphasis on team approach leverages the extensive experience and expertise of various specialists, thereby providing patients with evidence-based, yet individualized care, tailored not just to the cancer but also the patient’s unique physical, emotional and psychosocial needs.
Researchers at the Tata Memorial Centre are world leaders in basic, translational, epidemiologic and clinical cancer research. Research at TMC includes studies to understand cancer biology, large community based screening trials for common cancers and cohort studies, neoadjuvant and adjuvant treatment, perioperative interventions, surgical trials, repurposing drugs and qualitative research to understand the patient journey. Our research focuses on impacting survival and quality of life i.e., living longer, or living better –endpoints that really matter to patients.
Training and education form a major focus area for TMC, which remains the most sought after institution for oncology training nationally. Combining a world-class academic faculty and being amongst the highest volume cancer centres in the world, we take special pride that our alumni now provide specialist oncology care and hold leadership positions in several cancer centres in the country and internationally.

3. Tata Memorial Hospital Based Cancer Registry
1941
Hospital-Based Cancer Registry (HBCR) is functional since inception of the hospital
Several clinical and survival studies were published utilizing the HBCR data. Due to non-existence of computers, all statistical analysis was done manually using 80-coulmn punch cards, Sorting machines and Calculators
1963
Mumbai Cancer Registry was established in the premises of Tata Memorial Hospital (TMH) under Indian Cancer Society. All technical and administrative assistance was provided by TMH.
1982
Technical Wing of the National Cancer Registry Programme (NCRP), Indian Council of Medical Research (ICMR) was established in TMH premises
1985
Cancer Registry software was developed and Online data entry initiated. HBCR of TMH joined the network of National Cancer Registry Programme (NCRP) of Indian Council of Medical Research (ICMR).
Annual submission of data to NCRP was initiated from the year 1987.
The first Report of the TMH HBCR-NCRP network effort of registered cases seen in TMH was published in the year 1987.

4. Trend of All Cancers
Source: HBCR, Tata Memorial Hospital , Mumbai

5. Trend of Cancer by Residence
Source: HBCR, Tata Memorial Hospital , Mumbai

6. Head & Neck Cancers - Male
Site
% Change
Hypopharynx
6.9
Larynx
3.4
Oral Cavity
9.3 
Oropharynx
8.7
Source: HBCR, Tata Memorial Hospital , Mumbai

7. Head & Neck Cancers - Male
Site
% Change
Nasopharynx
0.4
Para Nasal Sinus
0.6
Salivary Gland (Major)
0.1
Source: HBCR, Tata Memorial Hospital , Mumbai

8. Head & Neck Cancers - Female
Site
% Change
Hypopharynx
1.7
Nasopharynx
0.0
Oral Cavity
0.4 
Oropharynx
1.0
Source: HBCR, Tata Memorial Hospital , Mumbai

9. Head & Neck Cancers - Female
Site
% Change
Larynx
0.2 
Para Nasal Sinus
0.7
Salivary Gland (Major)
0.1
Source: HBCR, Tata Memorial Hospital , Mumbai

10. Gastrointestinal Cancers - Male
Site
% Change
Colon
1.0 
Gall Bladder
2.8
Oesophagus
4.8
Pancreas
1.2
Source: HBCR, Tata Memorial Hospital , Mumbai

11. Gastrointestinal Cancers - Male
Site
% Change
Anal Canal
0.1 
Liver
1.6
Rectum
1.0
Small Intestine
0.2
Stomach
1.2
Source: HBCR, Tata Memorial Hospital , Mumbai

12. Gastrointestinal Cancers - Female
Site
% Change
Colon
1.0
Gall Bladder
5.5
Liver
0.6
Oesophagus
2.5 
Source: HBCR, Tata Memorial Hospital , Mumbai

13. Gastrointestinal Cancers - Female
Site
% Change
Anal Canal
0.1
Pancreas
1.0
Rectum
0.7
Stomach
0.6
Source: HBCR, Tata Memorial Hospital , Mumbai

14. Genito-Urinary Cancers - Male
Site
% Change
Kidney
1.0
Urinary Bladder
1.1
Prostate
1.9
Testis
0.5 
Penis
0.1
Source: HBCR, Tata Memorial Hospital , Mumbai

15. Genito-Urinary Cancers - Female
Site
% Change
Kidney
0.3
Urinary Bladder
0.1
Cervix
21.5 
Ovary
2.4
Corpus Uteri
1.1
Source: HBCR, Tata Memorial Hospital , Mumbai

16. Hematolymphoid Malignancies- Male
Site
% Change
Leukemia
0.9
Multiple Myeloma
0.6
Non-Hodgkins Lymphoma
0.8
Hodgkins Disease
Source: HBCR, Tata Memorial Hospital , Mumbai

17. Hematolymphoid Malignancies- Female
Site
% Change
Leukemia
1.2
Multiple Myeloma
0.2
Non-Hodgkins Lymphoma
Hodgkins Disease
0.3 
Source: HBCR, Tata Memorial Hospital , Mumbai

18. Trends in Common Cancers
Site
% Change
Head & Neck
7.0
Breast
5.8
Cervix
21.5
Years
Source: HBCR, Tata Memorial Hospital , Mumbai

19. Comparison with other HBCRs – 1984-1993
Source: NCDIR, India

20. Comparison with other HBCRs – 1999-2003
Source: NCDIR, India

21. Clinical Extent of Disease – Head & Neck Cancers
Source: HBCR, Tata Memorial Hospital , Mumbai

22. Trends in Treatment Modalities – Head & Neck Cancers
1985
1994
1999
1989
2004
2009
2014

23. Clinical Extent of Disease – Breast Cancer
Source: HBCR, Tata Memorial Hospital , Mumbai

24. Trends in Treatment Modality – Breast Cancer
1985
1994
1999
1989
2004
2009
2014
Source: HBCR, Tata Memorial Hospital , Mumbai

25. Clinical Extent of Disease at time of presentation at TMH – Cervix Cancer
Source: HBCR, Tata Memorial Hospital , Mumbai

26. Trends in Treatment Modality – Cervix Cancer
1985
1994
1999
1989
2004
2009
2014
Source: HBCR, Tata Memorial Hospital , Mumbai

27. Downstaging of Cervical Cancer over the years
Source: HBCR, Tata Memorial Hospital , Mumbai

28. Bone Marrow Transplants at TMH
Years
Source: HBCR, Tata Memorial Hospital , Mumbai

30. Thank you