1. Effects of an epigenetic diet.
Effects of an epigenetic diet. Consumption of foods that modulate epigenetic mechanisms has been shown to decrease the incidence of cancer and increase longevity, as well as prevent the onset of other age-related diseases. Cruciferous vegetables, such as broccoli, which are rich in sulforaphane, can act as HDAC inhibitors, regulating certain cancer-related genes. Genistein, which is found in soy beans, also exhibits chemopreventive properties and can result in both the partial reversal of aberrant DNA hypermethylation and the regulation of key miRNAs. Grapes contain resveratrol, a phenol that activates SIRT1 (a known HDAC inhibitor) and increases longevity, mimicking the effects of caloric restriction.
Michael Daniel, and Trygve O. Tollefsbol J Exp Biol 2015;218:59-70
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