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Baseline Q Waves and Time From Symptom Onset to ST-segment Elevation Myocardial Infarction: Insights From PLATO on the Influence of Sex Naji Kholaif, MD, Yinggan Zheng, MA, MEd, Pushpa Jagasia, MD, Anders Himmelmann, MD, Stefan K. James, MD, PhD, Philippe Gabriel Steg, MD, Robert F. Storey, MD, DM, Cynthia M. Westerhout, PhD, Paul W. Armstrong, MD The American Journal of Medicine Volume 128, Issue 8, Pages 914.e e19 (August 2015) DOI: /j.amjmed Copyright © 2015 Elsevier Inc. Terms and Conditions
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Figure 1 Patient cohort. ECG = electrocardiogram; LBBB = left bundle branch block; MI = myocardial infarction; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction. The American Journal of Medicine , 914.e e19DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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Figure 2 (A) Time from symptom onset to electrocardiogram (ECG; per hour) in men and women. (B) Baseline Q waves according to time from symptom onset to ECG for men and women. The American Journal of Medicine , 914.e e19DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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Figure 3 Associations of baseline Q waves and time to PCI on vascular mortality within 1 year in men and women. P(interaction, sex and baseline Q waves) = .509; P(interaction, sex and time to PCI) = A = adjusted; CI = confidence interval; HR = hazard ratio; PCI = percutaneous coronary intervention; pts = patients; U = unadjusted. *Adjusted for age, systolic blood pressure, heart rate, Killip Class, inferior myocardial infarction. The American Journal of Medicine , 914.e e19DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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Figure 4 Associations of baseline Q waves and sex on vascular mortality within 1 year according to time to PCI as a continuous variable; P(interaction, sex, and baseline Q waves and time to PCI) = For women with time = 8 hours, 95% CI, ; with time = 9 hours, 95% CI, ; with time = 10 hours, 95% CI, ; with time = 11 hours, 95% CI, ; with time = 12 hours, 95% CI, CI = confidence interval; HR = hazard ratio; PCI = percutaneous coronary intervention. *Adjusted for age, systolic blood pressure, heart rate, Killip Class, inferior myocardial infarction. The American Journal of Medicine , 914.e e19DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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Supplementary Figure Time from symptom onset to percutaneous coronary intervention (PCI) per hour on patients with time available in the PLATelet inhibition and patient Outcomes trial (PLATO; n = 4341, median 4.7 [ ]). The American Journal of Medicine , 914.e e19DOI: ( /j.amjmed ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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