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Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural.

Published byClifton Perkins Modified over 5 years ago

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Presentation on theme: "Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural."— Presentation transcript:

1 Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection  David J. Sugarbaker, MD, Ritu R. Gill, MD, Beow Y. Yeap, ScD, Andrea S. Wolf, MD, MPH, Marcelo C. DaSilva, MD, Elizabeth H. Baldini, MD, MPH, Raphael Bueno, MD, William G. Richards, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 145, Issue 4, Pages (April 2013) DOI: /j.jtcvs Copyright © Terms and Conditions

2 Figure 1 Kaplan-Meier survival functions for hyperthermic intraoperative cisplatin chemotherapy (HIOC) and comparison groups depicting interval to recurrence for (A) all patients, (B) patients who received adjuvant or neoadjuvant chemotherapy but no adjuvant radiotherapy, (C) patients who received adjuvant or neoadjuvant chemotherapy and adjuvant radiotherapy, (D) patients with N1 or N2 lymph node metastasis demonstrated on final pathologic examination, and (E) patients with N0 status determined by final pathologic examination. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

3 Figure 2 Kaplan-Meier survival functions for hyperthermic intraoperative cisplatin chemotherapy (HIOC) and comparison groups depicting overall survival for (A) all patients, (B) patients who received adjuvant or neoadjuvant chemotherapy but no adjuvant radiotherapy, (C) patients who received adjuvant or neoadjuvant chemotherapy and adjuvant radiotherapy, (D) patients with N1 or N2 lymph node metastasis demonstrated on final pathologic examination, and (E) patients with N0 status determined by final pathologic examination. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

4 Figure 3 Kaplan-Meier survival functions for hyperthermic intraoperative cisplatin chemotherapy (HIOC) and comparison groups depicting (A) interval to recurrence and (B) overall survival for patients found to have biphasic subtype tumors on final pathologic examination. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

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