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Peter M. Elias  Journal of Investigative Dermatology 

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Presentation on theme: "Peter M. Elias  Journal of Investigative Dermatology "— Presentation transcript:

1 The Epidermal Permeability Barrier: From the Early Days at Harvard to Emerging Concepts 
Peter M. Elias  Journal of Investigative Dermatology  Volume 122, Issue 2, Pages xxxvi-xxxix (February 2004) DOI: /j X x Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Endogenous pathways of SC acidification: regulated functions.. Journal of Investigative Dermatology  , xxxvi-xxxixDOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Proposed pH-dependent role of different proteases in desquamation.. Journal of Investigative Dermatology  , xxxvi-xxxixDOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Functions potentially impacted by filaggrin metabolism in SC.. Journal of Investigative Dermatology  , xxxvi-xxxixDOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

5 Figure 4 Cutaneous stress test: applications..
Journal of Investigative Dermatology  , xxxvi-xxxixDOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

6 Figure 5 Cutaneous stress test reveals additional risk factors..
Journal of Investigative Dermatology  , xxxvi-xxxixDOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions


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