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Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study  Gwinnett Ladson,

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Presentation on theme: "Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study  Gwinnett Ladson,"— Presentation transcript:

1 Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study  Gwinnett Ladson, M.D., William C. Dodson, M.D., Stephanie D. Sweet, M.D., Anthony E. Archibong, Ph.D., Allen R. Kunselman, M.A., Laurence M. Demers, Ph.D., Peter A. Lee, M.D., Ph.D., Nancy I. Williams, Sc.D., Ponjola Coney, M.D., Richard S. Legro, M.D.  Fertility and Sterility  Volume 95, Issue 8, Pages e6 (June 2011) DOI: /j.fertnstert Copyright © Terms and Conditions

2 Figure 1 (A) Changes in total serum testosterone, (B) Free Androgen Index (FAI), (C) acne lesion count, and (D) weight over 6 months by treatment arm. Metformin = combined metformin and lifestyle; Placebo = lifestyle and metformin. ∗P<.05 for a within-group change from baseline, † P<.05 for a between-group comparison at a given month. Fertility and Sterility  , e6DOI: ( /j.fertnstert ) Copyright © Terms and Conditions

3 Supplemental Figure 1 Flow chart of study participants in the trial.
Fertility and Sterility  , e6DOI: ( /j.fertnstert ) Copyright © Terms and Conditions

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