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Esophageal eosinophilia caused by milk proteins: From suspicion to evidence based on 2 case reports  Soledad Terrados Cepeda, MD, Dario Antolin-Amerigo,

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Presentation on theme: "Esophageal eosinophilia caused by milk proteins: From suspicion to evidence based on 2 case reports  Soledad Terrados Cepeda, MD, Dario Antolin-Amerigo,"— Presentation transcript:

1 Esophageal eosinophilia caused by milk proteins: From suspicion to evidence based on 2 case reports 
Soledad Terrados Cepeda, MD, Dario Antolin-Amerigo, MD, Jose Ramóm Foruny, MD, Ana Saiz Gonzalez, MD  Journal of Allergy and Clinical Immunology  Volume 129, Issue 5, Pages (May 2012) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 A and C, Patient 1 before challenge. Blocks were stained with hematoxylin and eosin, and immunohistochemistry was performed with anti-tryptase (CMA890, Cell Marque). B and D, Patient 1's biopsy specimens 48 hours after double-blind, placebo-controlled oral challenge with milk. Staining was with hematoxylin and eosin, and immunohistochemistry was performed with anti-tryptase (CMA890, Cell Marque). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Patient 2: basal esophageal endoscopic appearance. A, Eosinophils in patient 2 before challenge. The block was stained with hematoxylin and eosin showing eosinophils. B, Eosinophils in patient 2 after challenge. The block was stained with hematoxylin and eosin showing eosinophils. C, Mast cells in patient 2 before challenge. Immunohistochemistry was performed with anti-tryptase (CMA890, Cell Marque). D, Mast cells in patient 2 after challenge. Immunohistochemistry was performed with anti-tryptase (CMA890, Cell Marque). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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