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Bacterial endotoxin (LPS)–induced DNA damage in preimplanting embryonic and uterine cells inhibits implantation  Yogesh Kumar Jaiswal, Ph.D., Mukesh Kumar.

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Presentation on theme: "Bacterial endotoxin (LPS)–induced DNA damage in preimplanting embryonic and uterine cells inhibits implantation  Yogesh Kumar Jaiswal, Ph.D., Mukesh Kumar."— Presentation transcript:

1 Bacterial endotoxin (LPS)–induced DNA damage in preimplanting embryonic and uterine cells inhibits implantation  Yogesh Kumar Jaiswal, Ph.D., Mukesh Kumar Jaiswal, M.Sc., Varkha Agrawal, M.Sc., Madan Mohan Chaturvedi, Ph.D.  Fertility and Sterility  Volume 91, Issue 5, Pages (May 2009) DOI: /j.fertnstert Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Photomicrographs of embryos recovered from control and LPS-treated nonsuperovulated pregnant mice killed at different stages of preimplantation subjected to comet assay; ×10 magnification. Panels A, C, E, and G show comets of embryos collected from control animals killed at 1.5, 2.5, 3.5, and days of gestation, respectively. Panels B, D, F, and H show comets of embryos collected from LPS-treated animals killed at 1.5, 2.5, 3.5, and days of gestation, respectively. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Photomicrographs of uterine cells recovered from control and LPS-treated pregnant mice killed at different stages of preimplantation of pregnancy subjected to comet assay; ×40 magnification. Panels A, C, E, and G show comets of uterine cells from control animals killed at 1.5, 2.5, 3.5, and days of gestation, respectively. Panels B, D, F, and H show comets of uterine cells from LPS-treated animals killed at 1.5, 2.5, 3.5, and days of gestation, respectively. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions


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