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Published byΑἴαξ Ελευθερόπουλος Modified over 5 years ago
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Evaluation of endometrial biomarkers for semi-invasive diagnosis of endometriosis
Cleophas M. Kyama, Ph.D., Attila Mihalyi, Ph.D., Olivier Gevaert, Ph.D., Etienne Waelkens, M.D., Ph.D., Peter Simsa, M.Sc., Raf Van de Plas, Ph.D., Christel Meuleman, M.D., Bart De Moor, Ph.D., Thomas M. D'Hooghe, M.D., Ph.D. Fertility and Sterility Volume 95, Issue 4, Pages e3 (March 2011) DOI: /j.fertnstert Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions
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Figure 1 Women with endometriosis versus controls during luteal phase. Endometrial protein-peptide expression of kDa (fold difference [n-fold] = 2.5), kDa (n-fold = 1.64), kDa (n-fold = 1.32), kDa (n-fold = 1.52), and kDa (n-fold = 1.8) was significantly lower in women with endometriosis when compared with the controls. ∗P<.05; ∗∗P<.01; ∗∗∗P<.005. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions
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Figure 2 Women with minimal-mild endometriosis versus controls during luteal phase. Endometrial protein expression of kDa (fold difference [n-fold] = 2.0) and kDa (n-fold = 1.7) was significantly higher in women with minimal-mild endometriosis compared with controls. Decreased endometrial peptide levels for kDa (n-fold = 1.8) and kDa (n-fold = 3.0) in women with minimal-mild endometriosis were observed compared with controls. ∗P<.05; ∗∗P<.01. Stg = stage. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions
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Women with moderate-severe endometriosis versus controls during luteal phase. Increased endometrial protein levels for kDa (fold difference [n-fold] = 1.53) in women with moderate-severe endometriosis when compared with controls. Protein and peptide levels of kDa (n-fold = 1.9), kDa (n-fold = 2.33), and kDa (n-fold = 2.9) were significantly lower in endometrium of women with moderate-severe endometriosis when compared with controls. ∗P<.05; ∗∗P<.01; ∗∗∗P<.005. Fertility and Sterility , e3DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions
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