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Complete Response of Anaplastic Lymphoma Kinase–Mutated Refractory Extranodal Natural Killer/T-Cell Lymphoma to Crizotinib  Gita Thanarajasingam, MD,

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Presentation on theme: "Complete Response of Anaplastic Lymphoma Kinase–Mutated Refractory Extranodal Natural Killer/T-Cell Lymphoma to Crizotinib  Gita Thanarajasingam, MD,"— Presentation transcript:

1 Complete Response of Anaplastic Lymphoma Kinase–Mutated Refractory Extranodal Natural Killer/T-Cell Lymphoma to Crizotinib  Gita Thanarajasingam, MD, Eric S. Edell, MD, Svetomir M. Markovic, MD, PhD  Mayo Clinic Proceedings  Volume 91, Issue 9, Pages (September 2016) DOI: /j.mayocp Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure Response to crizotinib in a patient with anaplastic lymphoma kinase–positive extranodal natural killer/T-cell lymphoma, nasal type, documented on positron emission tomography (PET) and bronchoschopy. A, PET before initiation of crizotinib, showing tumor-related plaquelike hypermetabolism of left main stem bronchus. B, Metabolic response of endobronchial tumor on PET after 6 weeks of crizotinib. C, Tumor occlusion of the left main stem bronchus before initiation of crizotinib. D, Bronchoscopic view of main carina; silicone stent in left main stem bronchus on day 7 of crizotinib. E, Bronchoscopic view of main carina; biopsy was negative for recurrent disease after 6 weeks of crizotinib therapy. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions


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