1. IMI – an opportunity to implement research for patients and with patients
Catherine Brett
European Parliament Interest Group on Allergy and Asthma • Brussels, Belgium

2. Outline What is IMI? How are patients involved? U-BIOPRED EUPATI
PARADIGM
IMI and patients – an evolving story
An invitation!

3. What is IMI?

4. IMI – Europe’s partnership for health
> €5 bn
€2.5 bn
€2.5 bn
Partnership

5. Goals of IMI2 programme
Improve the drug development process by creating tools to assess the efficacy, safety and quality of medicines
Develop biological markers to diagnose diseases and assess treatments
Speed up the earlier stages of drug development
Increase the success rate of clinical trials of priority medicines
Develop new therapies for diseases with a high unmet need / limited market incentives
Reduce the failure rate of vaccine candidates in clinical trials

6. How are patients involved in IMI?

8. U-BIOPRED – breathing new life into severe asthma research
The biggest and most complex research project undertaken to understand severe asthma to date.
Main achievements:
uncovered a number of subtypes of severe asthma – this is already paving the way for the development of more effective treatments;
registry with data from patients including children & adults;
biobank with severe asthma patient samples (e.g. blood, sputum, lung tissue, urine), available for future research;
exemplary patient involvement! (and lessons being shared).
made a groundbreaking step forward in understanding asthma by uncovering a number of subtypes of severe asthma – this is already paving the way for the development of more effective treatments;
built a registry with data from patients belonging to eight different cohorts, some of which have never been studied before – an asset in future research;
built a biobank with more than severe asthma patient samples (e.g. blood, sputum, lung tissue, urine), also available for future research;
exemplary patient involvement!

9. EUPATI graduates - making a difference
58 disease areas, 31 countries
More & deeper involvement in R&D thanks to EUPATI
Sustainability (course, toolbox maintained by EPF)
‘Now we can speak with conviction & determination’
- Lara Stone

10. PARADIGM – for better patient engagement in medicines development
Mission
provide a unique framework that enables structured, effective, meaningful, ethical, innovative, and sustainable patient engagement and demonstrates the ‘return on engagement’ for all players
Objectives
develop processes and tools for three key decision-making points: research priority setting, design of clinical trials and early dialogue.
integrate the needs, perspectives and expectations of all actors (including vulnerable populations) involved and produce metrics to measure the impact of patient engagement.

11. IMI and patients

12. IMI and patients - an evolving story
Patient-focused projects
Patients as full IMI project partners (receiving funding)
Patients on project committees
Patients as IMI2 Associated Partners (contributing resources)
Patients on IMI Scientific Committee
Patients as speakers at IMI events
Hired a full-time patient engagement expert - NEW
Current goals:
Design & implement framework for deeper, more meaningful patient engagement in IMI.

13. Join us for our Scientific Symposium & Stakeholder Forum
IMI Scientific Symposium
Towards personalised medicines | Patient-centric approaches | Enablers for drug discovery & development | Collaborating to fight infections
22-23 October IMI Stakeholder Forum
The value of cross-sector health research & innovation
24 October 2018
Brussels, Belgium
Registration via
#IMITenYears #IMICarryTheTorch

14. Catherine Brett • External Relations Manager
Thank you
Catherine Brett • External Relations Manager