1. Volume 128, Issue 3, Pages 564-573 (March 2005)
Regional brain activation during proximal stomach distention in humans: A positron emission tomography study 
Joris Vandenbergh, Patrick DuPont, Benjamin Fischler, Guy Bormans, Philippe Persoons, Jozef Janssens, Jan Tack 
Gastroenterology 
Volume 128, Issue 3, Pages (March 2005)
DOI: /j.gastro
Copyright © 2005 American Gastroenterological Association Terms and Conditions

2. Figure 1
Rendered image of the right lateral, left lateral, and inferior view of the mean activation pattern during maximal distention relative to baseline (subtraction analysis: maximal distention condition − baseline condition). Analysis was run at the Puncorrected < .001 level. O, occipital; F, frontal.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

3. Figure 2
Right sagittal section (mean MRI image; section 6 mm from median as demonstrated in the right image) through clusters with increased activation in the right anterior cingulate gyrus (BA 24) and the right thalamus, showing the mean activation pattern during maximal distention relative to baseline (subtraction analysis: maximal distention condition − baseline condition). Analysis was run at the Puncorrected < .001 level. Only the activation of the anterior cingulate gyrus was significant at the Pcorrected < .05 level. F, frontal; O, occipital; L, left; R, right.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Right horizontal section (mean MRI image; section at −2 mm as demonstrated in the right image) through clusters with increased activation in the right insula (anterior part), the right thalamus, and bilateral gyri postcentralis. This shows the activation pattern during maximal distention relative to baseline (subtraction analysis: maximal distention condition − baseline condition). Analysis was run at the Puncorrected < .001 level. Only the activation of the insula was significant at the Pcorrected < .05 level. F, frontal; O, occipital; L, left; R, right.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

5. Figure 4
A) The evolution of the mean distending pressure (n = 11; mm Hg above minimal distending pressure; y-axis to the right) throughout the 4 conditions (control, first sensation, marked sensation, and maximal distention). (B–I) The mean change of PET signal (relative to the signal in the control condition; y-axis to the left) throughout the 4 conditions in the 8 coordinates listed in Table 1: right gyrus postcentralis (B, coordinate 52, 36, −22), left gyrus temporalis superior (C, coordinate −48, 20, −38), right gyrus precentralis (D, coordinate 68, 6, 2), left gyrus postcentralis (E, coordinate −64, 2, 8), right gyrus postcentralis (F, coordinate 70, 0, 12), left cerebellar hemisphere (G, coordinate −48, −76, −32), right insula (H, coordinate 34, 14, −2), and right anterior cingulate gyrus (I, coordinate 12, 26, 22).
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions