1. Serenoa repens: The Scientific Basis for the Treatment of Benign Prostatic Hyperplasia 
Fouad K. Habib 
European Urology Supplements 
Volume 8, Issue 13, Pages (December 2009)
DOI: /j.eursup
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2. Fig. 1
(a) Electron micrographs of untreated cocultured fibroblast cells. Micrograph A (×3888) shows characteristic elongated nuclei (N), high levels of Golgi apparatus (G), and cilia. Micrograph B (×86 400) shows a collagen fibril (F) produced by the cocultured fibroblast cells. (b) Electron micrographs of Serenoa repens extract (SrE)–treated (10μg/ml) cocultured fibroblast cells. Micrograph A (×15 984) shows general disruption of the cell cytoplasm and accumulation of lipids (L) in the cell. Micrograph B shows damage to the Golgi apparatus (G) in a fibroblast cell treated with SrE [5].
European Urology Supplements 2009 8, DOI: ( /j.eursup )
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3. Fig. 2
Effect of a 5-d treatment with Serenoa repens extract (SrE) (10μg/ml) on the activity of 5α-reductase types I (5α-R1) and II (5α-R2) in cocultured epithelial and fibroblast cells. Each data set is the result of three separate experiments. Results are expressed as means plus or minus standard error of the mean [5].
DHT=dihydrotestosterone.
European Urology Supplements 2009 8, DOI: ( /j.eursup )
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4. Fig. 3
Effect of a 2-d treatment with Serenoa repens extract (10μg/ml) on the activity of 5α-reductase types I and II in primary cultured cells from prostate, skin, breast, epididymis, testes, and kidney [13].
European Urology Supplements 2009 8, DOI: ( /j.eursup )
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5. Fig. 4
Visual representation of the content of 14 brands of SrE, as determined by analysis [3].
FFA=free fatty acids.
European Urology Supplements 2009 8, DOI: ( /j.eursup )
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6. Fig. 5
Schematic diagram showing some of the Serenoa repens extract (SrE) targets at the level of the prostate cell.
DHT=dihydrotestosterone; EGF=epidermal growth factor; FGF=fibroblast growth factor.
European Urology Supplements 2009 8, DOI: ( /j.eursup )
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