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Volume 54, Issue 2, Pages 608-617 (August 1998)
Compositional and functional changes of low-density lipoprotein during hemodialysis in patients with ESRD1 Andreas Ambrosch, Ute Domroese, Sabine Westphal, Jutta Dierkes, Wolfgang Augustin, Klaus H. Neumann, Claus Luley Kidney International Volume 54, Issue 2, Pages (August 1998) DOI: /j x Copyright © 1998 International Society of Nephrology Terms and Conditions
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Figure 1 Inverse correlations between the size of the major low-density lipoprotein (LDL) subfractions (nm) and the triglyceride (TG) content per particle (A; r = 0.42, P < 0.02) and the relationship between LDL size and unesterified cholesterol (FC) per apoB ratios (B; r = 0.40, P < 0.04) in normo- and hypertriglyceridemic patients. (C) Inverse correlation between cholesteryl ester content per particle and the triglyceride content in LDL within normo- (NTG; ▴) and hypertriglyceridemic (HTG; □) study participants (r = -0.37, P < 0.05). Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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Figure 2 Changes in the triglyceride content per apoB during hemodialysis (expressed as ΔLDL-TG/apoB) are positively related to the changes in the LDL diameter (expressed as ΔLDL-diameter). Symbols are: (□) hypertriglyceridemic and (▴) normoglyceridemic subjects. r = 0.38, P < 0.05. Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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Figure 3 CETP activities before, during (1.5hr after the bolus heparinization at the beginning of hemodialysis) and after hemodialysis therapy in normo- (NTG; ▴) and hypertriglyceridemic (HTG; □) patients. Each time point represents the median values with minimum and maximum. #P < 0.001, NTG vs. HTG group; *P < 0.01 and **P < vs. baseline levels within each study group. Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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Figure 4 Cellular [3H]-oleate incorporation into cholesteryl ester in fibroblasts (A) and murine macrophages P388 (B) induced by LDL prepared from NTG and HTG patients before [HTG-LDL (▪) and NTG-LDL (▾) and during hemodialysis [HTG-LDL (hemodialysis) (□) and NTG-LDL (hemodialysis) (▵)]. #P < 0.05, between NTG-LDL and the corresponding HTG-LDL concentration; *P < 0.05, between hemodialysis-modified LDL and baseline LDL within each group and LDL concentration. Values are mean ± sd. Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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Kidney International 1998 54, 608-617DOI: (10. 1046/j. 1523-1755. 1998
Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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Kidney International 1998 54, 608-617DOI: (10. 1046/j. 1523-1755. 1998
Kidney International , DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions
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