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Effects of in vivo AICAR treatment on blood glucose and lactate concentrations.
Effects of in vivo AICAR treatment on blood glucose and lactate concentrations. Rats were given an intraperitoneal injection of AICAR (0.85 mg/g), and blood was collected for 120 min afterward for determination of glucose (A) and lactate (B) concentrations. Blood glucose was reduced from basal levels of ∼111 mg/dl by 25–50 mg/dl throughout the 120-min postinjection time period. Blood lactate was also markedly increased after AICAR treatment. *P < 0.05 vs. basal; n = 4–5 per time point. William G. Aschenbach et al. Diabetes 2002;51: ©2002 by American Diabetes Association
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