1. It’s ALL in the Family: IKZF1 and Hereditary Leukemia
Junne Kamihara, Akiko Shimamura 
Cancer Cell 
Volume 33, Issue 5, Pages (May 2018)
DOI: /j.ccell
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2. Figure 1 IKZF1 Germline and Somatic Mutations
(A) IKZF1 structural domains and mutations (top), modified from Churchman et al. (2018), and functional assays used by Churchman et al. to assess pathogenicity of identified IKZF1 variants (bottom). (B) Germline IKZF1 mutations are associated with immunodeficiency and predisposition to B cell leukemia. Acquisition of somatic mutations in IZKF1 also promote the development of B cell leukemia. HSC, hematopoietic stem cell. Figure 1B modified from
Cancer Cell  , DOI: ( /j.ccell )
Copyright © 2018 Elsevier Inc. Terms and Conditions