1. NOAH: pCR Results Patients (%) P=0.002 P=0.003 P=0.29 P=0.43 With T
Without T
HER2 negative
With T
Without T
HER2 negative
HER2 positive
HER2 positive
pCR
Total pCR
T=trastuzumab
Adapted from Gianni et al. ASCO 2007, abstract 532.

2. ER Negative vs. Positive PgR Negative vs. Positive
pCR According to Receptor Status
Total pCR
ER Negative vs. Positive
PgR Negative vs. Positive
HER2 negative, no H
16%
32% vs. 6% (P=0.0007)
26% vs. 6% (P=0.007)
HER2 positive, no H
20%
22% vs. 17% (P=0.51)
23% vs. 12% (P=0.24)
HER2 positive, H
39%
48% vs. 18% (P=0.002)
48% vs. 11% (P=0.006)
Adapted from Eiermann et al. Eur J Cancer Suppl 2008;6(7):115, Abstract 228.