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Sufentanil administration guided by surgical pleth index vs standard practice during sevoflurane anaesthesia: a randomized controlled pilot study†  M.

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Presentation on theme: "Sufentanil administration guided by surgical pleth index vs standard practice during sevoflurane anaesthesia: a randomized controlled pilot study†  M."— Presentation transcript:

1 Sufentanil administration guided by surgical pleth index vs standard practice during sevoflurane anaesthesia: a randomized controlled pilot study†  M. Gruenewald, S. Willms, O. Broch, M. Kott, M. Steinfath, B. Bein  British Journal of Anaesthesia  Volume 112, Issue 5, Pages (May 2014) DOI: /bja/aet485 Copyright © 2014 The Author(s) Terms and Conditions

2 Fig 1 Characteristics for SPI (a), BIS (b), and end-tidal sevoflurane concentration (c) representing major time points during anaesthesia in the SPI (blue) and control (green) groups. Values are mean (sd). Baseline, before induction of anaesthesia; LOC, loss of consciousness; pre-intubation, before intubation; max intubation, maximum value during/after intubation; pre-incision, before start of surgery by incision; max incision, maximum value during/after incision (I); suture, final suture; E, extubation. ±values are in minutes. British Journal of Anaesthesia  , DOI: ( /bja/aet485) Copyright © 2014 The Author(s) Terms and Conditions

3 Fig 2 Time courses of SPI (blue) and HR (green) during time period 120 s before and after sufentanil administration (dashed line) in the SPI (a) and control (b) groups. Values are individual (dotted/thin lines) and mean (solid/bold lines). British Journal of Anaesthesia  , DOI: ( /bja/aet485) Copyright © 2014 The Author(s) Terms and Conditions

4 Fig 3 Box plots of recorded maximum change of SPI (blue) and HR (green stripes) in the time period of 2 min before and after unwanted somatic event (movement) in the SPI and control groups. British Journal of Anaesthesia  , DOI: ( /bja/aet485) Copyright © 2014 The Author(s) Terms and Conditions

5 Fig 4 Kaplan–Meier curves for cumulative probability of patients remaining eyes not open after end of surgery (final suture) in the SPI (blue, filled area) and control (green) groups. British Journal of Anaesthesia  , DOI: ( /bja/aet485) Copyright © 2014 The Author(s) Terms and Conditions


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