1. Microscopic morphology of Rhizopusspp. , Aspergillus spp
Microscopic morphology of Rhizopusspp., Aspergillus spp., and Candida spp. in tissue.
Microscopic morphology of Rhizopusspp., Aspergillus spp., and Candida spp. in tissue. (A) Rhizopus spp. in tissue section stained with GMS. The mucoraceous zygomycetes produce wide ribbon-like aseptate hyphae in tissues. There is a great deal of variation of hyphal width. Branching occurs at wide angles nearing 90° (arrowheads). A frothy or bubbly tissue appearance may be seen in areas of tissue where the hyphae are cross-sectioned (upper left hand corner of the frame). (B)Aspergillus spp. in tissue section stained with GMS.Aspergillus spp. produce thin hyphae with relatively consistent diameters. Hyphae are septate, with no constriction of the fungus seen at the point of septation (arrowheads). Blastoconidia are not produced, although areas where hyphae are cross-sectioned may be confused with yeast cells (asterisk). Hyphae branch at acute angles of about 45° (arrow). (C) Candida spp. in tissue section stained with GMS. Fungal elements in tissue appear as pseudohyphae with blastoconidia. Fungal elements constrict or “bud” at sites of septation (arrowheads). Branching occurs at acute angles (arrow). Pseudohyphae are thin, and their diameter is very similar to that seen for the true hyphae of the Aspergillus spp. All three panels are the same magnification. Bar, 10 μm.
Julie A. Ribes et al. Clin. Microbiol. Rev. 2000; doi: /CMR