1. Ado loss alters cellular metabolism.
Ado loss alters cellular metabolism. Control or Ado knockout MC38 cells were subjected to amine derivatization/liquid chromatography–MS (cysteamine, cystamine, taurine, and glutathione) and GC-MS polar metabolomics (cystamine, taurine, cysteine, and hypotaurine). ATP, adenosine 5′-triphosphate; ADP, adenosine 5′-diphosphate; AMP, adenosine 5′-monophosphate. *P < 0.01, **P < 0.001, ***P < , ****P < NS, not significant.
Conor J. Kearney et al. Sci. Immunol. 2018;3:eaar3451
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