Presentation is loading. Please wait.

Presentation is loading. Please wait.

Systems medicine-based approaches in interstitial lung diseases seek to analyse biological products (e.g. Systems medicine-based approaches in interstitial.

Published byChristiana Greer Modified over 5 years ago

Similar presentations

Presentation on theme: "Systems medicine-based approaches in interstitial lung diseases seek to analyse biological products (e.g. Systems medicine-based approaches in interstitial."— Presentation transcript:

1 Systems medicine-based approaches in interstitial lung diseases seek to analyse biological products (e.g. Systems medicine-based approaches in interstitial lung diseases seek to analyse biological products (e.g. RNA, DNA, proteins, metabolites, microbiome, etc.) and, through massive data generation and integration with clinical features, help to identify biomarkers that can predict disease phenotypes. OTU: operational taxonomic unit; MUC5B: mucin 5B; ICAM-1: intracellular adhesion molecule-1; MMP-7: metalloproteinase-7; TOLLIP: Toll-interacting protein; TERT: telomerase reverse transcriptase. Flavia R. Greiffo et al. Eur Respir Rev 2017;26:170021 ©2017 by European Respiratory Society

Download ppt "Systems medicine-based approaches in interstitial lung diseases seek to analyse biological products (e.g. Systems medicine-based approaches in interstitial."

Similar presentations

Kaplan–Meier survival curves of interstitial pneumonia with autoimmune features (IPAF) with usual interstitial pneumonia (UIP) pattern (on high-resolution.

Kaplan–Meier survival curves of interstitial pneumonia with autoimmune features (IPAF) with usual interstitial pneumonia (UIP) pattern (on high-resolution.
Longitudinal imaging after initial diagnosis

Longitudinal imaging after initial diagnosis
Discoidin domain receptor (DDR)2 protein was highly expressed in the lungs of patients with interstitial lung disease (ILD). Discoidin domain receptor.

Discoidin domain receptor (DDR)2 protein was highly expressed in the lungs of patients with interstitial lung disease (ILD). Discoidin domain receptor.
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
High-resolution computed tomography (HRCT) features of interstitial lung abnormalities. a) HRCT of a 56-year-old patient whose mother died of idiopathic.

High-resolution computed tomography (HRCT) features of interstitial lung abnormalities. a) HRCT of a 56-year-old patient whose mother died of idiopathic.
Radiology assessment of pulmonary amyloidosis

Radiology assessment of pulmonary amyloidosis
In chronic haemorrhage a) several pigmented macrophages fill the alveoli with dense fibrosis of the interstitium; b) the haemosiderin pigment in macrophages.

In chronic haemorrhage a) several pigmented macrophages fill the alveoli with dense fibrosis of the interstitium; b) the haemosiderin pigment in macrophages.
Conceptual framework of the interaction between environmental exposure including smoking, alpha-1 antitrypsin (AAT) level and/or AAT genotype, other genetic.

Conceptual framework of the interaction between environmental exposure including smoking, alpha-1 antitrypsin (AAT) level and/or AAT genotype, other genetic.
Flowchart showing the requirement for starting, documenting and evaluating the effect on quality of life (QoL) of interdisciplinary best supportive care.

Flowchart showing the requirement for starting, documenting and evaluating the effect on quality of life (QoL) of interdisciplinary best supportive care.
High-resolution computed tomography scan revealing a nonspecific interstitial pneumonia pattern with basal predominant ground-glass opacities and associated.

High-resolution computed tomography scan revealing a nonspecific interstitial pneumonia pattern with basal predominant ground-glass opacities and associated.
a) Chest radiograph showing bilateral coarse interstitial shadowing

a) Chest radiograph showing bilateral coarse interstitial shadowing
Representative photomicrograph of small airways abnormalities in a subject with chronic obstructive pulmonary disease. Representative photomicrograph of.

Representative photomicrograph of small airways abnormalities in a subject with chronic obstructive pulmonary disease. Representative photomicrograph of.
Extent of interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD. A simple stratification that utilises pulmonary function.

Extent of interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD. A simple stratification that utilises pulmonary function.
Different radiological “phenotypes” of bronchiectasis

Different radiological “phenotypes” of bronchiectasis
a) Schematic example of a basket trial.

a) Schematic example of a basket trial.
Electromagnetic navigation image: the icon representing the locatable guide (arrow) can be seen 3 mm away from the centre of a small pulmonary nodule in.

Electromagnetic navigation image: the icon representing the locatable guide (arrow) can be seen 3 mm away from the centre of a small pulmonary nodule in.
A) Healthcare utilisation, b) short form (SF)-12 scores and c) work productivity and activity impairment in patients with asthma (▓) and diabetes (▪) in.

A) Healthcare utilisation, b) short form (SF)-12 scores and c) work productivity and activity impairment in patients with asthma (▓) and diabetes (▪) in.
Nonspecific interstitial pneumonia fibrosing pattern in a case of connective tissue disease. a) The alveolar walls are thickened by interstitial fibrosis.

Nonspecific interstitial pneumonia fibrosing pattern in a case of connective tissue disease. a) The alveolar walls are thickened by interstitial fibrosis.
Radiodiagnostic imaging

Radiodiagnostic imaging
3-year survival of lung cancer patients in the general population and in those with a prior diagnosis of chronic obstructive pulmonary disease (COPD).

3-year survival of lung cancer patients in the general population and in those with a prior diagnosis of chronic obstructive pulmonary disease (COPD).

Similar presentations

Ads by Google