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The General Linear Model

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Presentation on theme: "The General Linear Model"— Presentation transcript:

1 The General Linear Model
Data Design Matrix filter intrinsic correlations and non-sphericity correction contrast images SPM{T}

2 SPM{T} isoluminant stimuli (even) isochromatic stimuli (odd) V5 speed

3 contrast 100 SPM{T} PPM 200 300 1 2 3 4 Design matrix z = 3mm z = 3mm

4 Temporal basis functions
Single HRF FIR model Stimulus function Design matrix SPM{F}

5 neuronal input hidden states hemodynamics BOLD response

6 Nonlinear saturation

7 Attention Photic SPC V1 IFG V5 Motion .52 (98%) .37 (90%) .42 (100%)
.56 (99%) V1 .69 (100%) IFG .47 (100%) ..82 (100%) V5 Motion .65 (100%)

8 inhibitory interneurons
Extrinsic lateral connections Extrinsic forward connections spiny stellate cells inhibitory interneurons pyramidal cells Intrinsic connections Extrinsic backward connections Neuronal model

9 inhibitory interneurons
spiny stellate cells inhibitory interneurons pyramidal cells Intrinsic Forward Backward Lateral time input .56/.61 .59/.87 .05/.04 .00/.09 .01/3.68 P300 Real and modelled frequent rare


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