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Figure 2 Cell-based assay demonstrating differential binding of AChR antibodies to the adult and fetal receptorsThe fetal (gamma subunit specific) and.

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Presentation on theme: "Figure 2 Cell-based assay demonstrating differential binding of AChR antibodies to the adult and fetal receptorsThe fetal (gamma subunit specific) and."— Presentation transcript:

1 Figure 2 Cell-based assay demonstrating differential binding of AChR antibodies to the adult and fetal receptorsThe fetal (gamma subunit specific) and adult (epsilon subunit specific) forms of the receptors were expressed in human embryonic kidney cells, identified with green fluorescence. Cell-based assay demonstrating differential binding of AChR antibodies to the adult and fetal receptorsThe fetal (gamma subunit specific) and adult (epsilon subunit specific) forms of the receptors were expressed in human embryonic kidney cells, identified with green fluorescence. Binding of immunoglobulin G was detected by anti-human IgG (red fluorescence). Results of a maternal serum from patient 3 that bound very weakly to the adult receptor (A), but strongly to the fetal receptor (B). Yael Hacohen et al. Neurol Neuroimmunol Neuroinflamm 2015;2:e57 © 2014 American Academy of Neurology

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