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Neoadjuvant and Adjuvant Chemotherapy in Resected Pulmonary Large Cell Neuroendocrine Carcinomas: A Single Institution Experience  Inderpal S. Sarkaria,

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Presentation on theme: "Neoadjuvant and Adjuvant Chemotherapy in Resected Pulmonary Large Cell Neuroendocrine Carcinomas: A Single Institution Experience  Inderpal S. Sarkaria,"— Presentation transcript:

1 Neoadjuvant and Adjuvant Chemotherapy in Resected Pulmonary Large Cell Neuroendocrine Carcinomas: A Single Institution Experience  Inderpal S. Sarkaria, MD, Akira Iyoda, MD, Mee Soo Roh, MD, Gabriel Sica, MD, PhD, Deborah Kuk, MS, Camelia S. Sima, MD, Maria C. Pietanza, MD, Bernard J. Park, MD, William D. Travis, MD, Valerie W. Rusch, MD  The Annals of Thoracic Surgery  Volume 92, Issue 4, Pages (October 2011) DOI: /j.athoracsur Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Advanced stage III/IV is associated with decreased overall survival in patients with resected large cell neuroendocrine carcinoma. (— = I; ··· = II; ·–· = III/IV.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Tumor T stage is associated with decreased overall survival in patients with resected large cell neuroendocrine carcinoma. (— = T1; ··· = T2; ·–· = T3/T4.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Tumor N stage is associated with decreased overall survival in patients with resected large cell neuroendocrine carcinoma. (— = 0; ··· = 1; ·–· = 2/3.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Male gender is associated with decreased overall survival in patients with resected large cell neuroendocrine carcinoma. (— = female; — = male.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Stage IB large cell neuroendocrine carcinoma is associated with decreased overall survival compared with stage IA. (— = IA; ··· = IB.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

7 Fig 6 Trend toward improved survival in patients with advanced stage IB–IIIA completely resected (R0) large cell neuroendocrine carcinomas treated with induction and (or) adjuvant platinum-based combination chemotherapy. (— = no; ··· = yes.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

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