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Published byReginald Holland Modified over 5 years ago
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In-Geol Choi, Jaimyoung Kwon, and Sung-Hou Kim, UC Berkeley
Local feature frequency profile: A method to measure structural similarity in proteins In-Geol Choi, Jaimyoung Kwon, and Sung-Hou Kim, UC Berkeley PNAS 2004 presented by Chao Wang
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Abstract
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Background Protein classification Protein alignment SCOP CATH DALI CE
VAST SSAP
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Background cont'd Protein structure universe
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Methods
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Database
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Local Feature (LF)
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LF cont'd
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SVD for visualization
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Results How to select the parameters? m=10, K=100
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100 clusters
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Why use normalization?
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Visualization
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Visualization cont'd
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Comparison with SCOP/CATH
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Special case
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Discussion
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Comments by Chao To design features in our NN ...
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