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The effect of inhaled tiotropium (18 μg once daily) on the improvement in treadmill exercise endurance time in patients with chronic obstructive pulmonary disease undergoing pulmonary rehabilitation exercise sessions. The effect of inhaled tiotropium (18 μg once daily) on the improvement in treadmill exercise endurance time in patients with chronic obstructive pulmonary disease undergoing pulmonary rehabilitation exercise sessions. Ninety-one patients received tiotropium or placebo for 4 weeks before, 8 weeks during and 12 weeks after a thrice-weekly rehabilitative exercise training programme. ▴: patients treated with tiotropium; \#9679;: patients treated with placebo. *: p<0.05. Reprinted from [34] with permission from the publisher. R. Casaburi Eur Respir Rev 2006;15:42-46 ©2006 by European Respiratory Society
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