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Membrane Structure
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1. Fat Soluble Molecules Examples: Fatty acids Passive Diffusion
Oxygen & carbon dioxide Alcohol & nicotine
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2. Water Moves by OSMOSIS through protein lined pores
Called AQUAPORINS Some water will passively diffuse (leak) through the membrane
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3. Transport by Carrier Molecules
A. FACILITATED TRANSPORT Also called passive transport Glucose & amino acids move in this way They are LIPID INSOLUBLE (need a carrier protein) Carrier proteins are reusable Very specific
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B. ACTIVE TRANSPORT Moves molecules against a concentration gradient Examples: Iodine collects in thyroid gland Glucose is completely absorbed by lining of intestine Need carrier proteins and ATP ENERGY!! Active transport cells high in mitochondria
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C. SODIUM POTASSIUM PUMP
Also needs carrier proteins and ATP Protein carrier changes shape to fit Na+, then K+ 3 Na+ move OUT of the cell; 2 K+ move IN
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Cell Size Individual cells maintain a HIGH surface area to volume ratio
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Example… Surface Area 6 units2 24 units2 Volume 1 unit3 8 units3 RATIO
Cell A (1x1x1) Cell B (2x2x2) Surface Area 6 units2 24 units2 Volume 1 unit3 8 units3 RATIO 6:1 HIGH ratio! 3:1 LOWER ratio
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WHY does cell size seek to optimize this ratio?
Cells with a large volume require more nutrients, oxygen, etc AND produce more wastes Membranes are limited to moving material in or out of the cell at a maximum rate More membrane = better ability to move materials in/out of cell!
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Membrane Structure Group Activity: Your group will be assigned a fact about cell membranes and the tasks they accomplish. Your job is to explain HOW a cell carries out your task and provide the class with a basic diagram and a short description.
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FACT: The concentration of water at the beginning of the large intestine is higher than at the end of the organ. However, the fatty part of the membrane is hydrophobic. EXPLANATION
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FACT: Virtually all glucose and amino acids in the foods you eat and digest are absorbed by the bloodstream. EXPLANATION
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FACT: Using electrical probes, scientists have determined that the part of a nerve cell at rest has a high Na+ concentration outside and high K+ concentration inside. When firing, Na+ and K+ trade places. EXPLANATION
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FACT: Cl- passively diffuses across membranes, yet it can’t move through lipids.
EXPLANATION
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FACT: Fatty acids and glycerol move freely across membranes.
EXPLANATION
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FACT: Hormones have specific target cells.
EXPLANATION
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FACT: White blood cells such as macrophages engulf whole viruses.
EXPLANATION
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FACT: Your immune system can recognize foreign antigens.
EXPLANATION
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FACT: Glucose passes across membranes many times faster than fructose.
EXPLANATION
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FACT: Cancer cells have lost “contact inhibition” and will grow into a mass.
EXPLANATION
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FACT: Cells can communicate with their neighbours.
EXPLANATION
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FACT: At the beginning of the filtration process, lots of glucose has left the blood and joined the potential urine. Kidney cells use up ATP when ensuring that your urine contains no glucose. EXPLANATION
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