1. The possible off-target effect of increased heart failure hospitalizations from saxagliptin in the SAVOR trial.
The possible off-target effect of increased heart failure hospitalizations from saxagliptin in the SAVOR trial. Higher N-terminal pro-B-type natriuretic peptide levels predicted increased risk for heart failure hospitalizations. The highest levels significantly increased this risk, but did not increase mortality. Most of the patients had a history of heart failure. Adapted from References 9 and 11.
Vani P. Sanon et al. Clin Diabetes 2014;32:
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