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Comparable Long-Term Survival after Bone Marrow versus Peripheral Blood Progenitor Cell Transplantation from Matched Unrelated Donors in Children with.

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Presentation on theme: "Comparable Long-Term Survival after Bone Marrow versus Peripheral Blood Progenitor Cell Transplantation from Matched Unrelated Donors in Children with."— Presentation transcript:

1 Comparable Long-Term Survival after Bone Marrow versus Peripheral Blood Progenitor Cell Transplantation from Matched Unrelated Donors in Children with Hematologic Malignancies  Roland Meisel, Hans-Jürgen Laws, Stefan Balzer, Benedikt Bernbeck, Christof Kramm, Stefan Schönberger, Kumar Sinha, Anja Tröger, Monika Schmitz, Johannes Fischer, Ulrich Göbel, Jürgen Enczmann, Dagmar Dilloo  Biology of Blood and Marrow Transplantation  Volume 13, Issue 11, Pages (November 2007) DOI: /j.bbmt Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Time to neutrophil and platelet engraftment. The cumulative probability of reaching neutrophil (A) and platelet (B) engraftment is shown for the PBPC group (dotted line) and BM group (solid line). N, number of patients evaluable in each arm of the study cohort; Ev, number of events (neutrophil/platelet engraftment) observed in each arm. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Incidence of aGVHD. The cumulative incidences of grade II-IV (A) and grade III-IV (B) aGVHD is shown for the PBPC group (dotted line) and BM group (solid line). N, number of evaluable patients in each arm of the study cohort; Ev, number of events (grade II-IV/III-IV aGVHD) observed in each arm. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Incidence of cGvHD. The cumulative incidences of any grade (A) and clinically extensive (B) cGVHD is shown for the PBPC group (dotted line) and BM group (solid line). N, number of evaluable patients in each arm of the study cohort; Ev, number of events (any grade/clinically extensive cGvHD) observed in each arm. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Probability of relapse-free survival (RFS) and overall survival (OS). RFS (A) and OS (B) is depicted for the PBPC group (dotted line) and BM group (solid line). N, number of patients in each arm of the study cohort; Ev, number of events observed in each arm. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

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