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Merging the Art and Science of Managing nOH in Clinical Practice

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Presentation on theme: "Merging the Art and Science of Managing nOH in Clinical Practice"— Presentation transcript:

1 Merging the Art and Science of Managing nOH in Clinical Practice

2 Definitions of OH and nOH

3 Pathophysiology of OH and nOH

4 Case Study

5 Patients in 5 Categories at Higher Risk for OH or nOH

6 Screening Questions for Suspected OH or nOH

7 How to Diagnose OH Features Suggestive of nOH

8 Diagnosis of nOH in Individuals Who Screen Positive for OH If the Diagnosis is OH and not nOH

9 Common Medications That May Cause OH or Exacerbate the Symptoms of nOH

10 Consensus Panel Recommendations Supine Hypertension and nOH

11 Treatment Algorithm for nOH

12 Treating nOH – Step 1 Review and Adjust Current Medications

13 Treating nOH – Step 2 Nonpharmacologic Measures

14 Treating nOH – Step 2 Nonpharmacologic Measures (cont)

15 Treating nOH – Step 2 Nonpharmacologic Measures (cont)

16 Treating nOH – Step 3 Initial Pharmacologic Treatment

17 Pharmacologic Options Fludrocortisone

18 Pharmacologic Options Midodrine

19 Pharmacologic Options Droxidopa

20 Pharmacologic Options Pyridostigmine

21 Mechanisms of Action of Investigational Therapies

22 Assessing nOH Treatment Success

23 Concluding Remarks

24 Abbreviations


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