1. Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with polycystic ovary syndrome 
Nathalie Neveu, M.D., Louis Granger, M.D., Pierre St-Michel, M.D., Hélène B. Lavoie, M.D. 
Fertility and Sterility 
Volume 87, Issue 1, Pages (January 2007)
DOI: /j.fertnstert
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2. FIGURE 1
Ovulation, pregnancy, and spontaneous abortion rates (sab) for patients taking CC (gray), metformin (black), or combination (white). Ovulation rate of patients taking metformin was significantly better than that of patients taking CC (*P=.005). Pregnancy and spontaneous abortion rates were equivalent in the three groups.
Neveu. Metformin and clomiphene citrate in PCOS women. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

3. FIGURE 2
Time to conception for patients taking CC (gray), metformin (black), or combination (white). Most patients taking CC conceived within first 6 months of therapy. Patients taking metformin alone or in combination conceived throughout first year of treatment. Some patients required over a year to conceive.
Neveu. Metformin and clomiphene citrate in PCOS women. Fertil Steril 2007.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions