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Propofol: Milk of Amnesia

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1 Propofol: Milk of Amnesia
Christopher T. Walsh  Cell  Volume 175, Issue 1, Pages (September 2018) DOI: /j.cell Copyright © 2018 Elsevier Inc. Terms and Conditions

2 Figure 1 Several Anesthetics Target the GABA Receptor
(A) Structures of morphine and several synthetic anesthetic agents. The in vivo metabolism of propofol to water-soluble glucuronides and sulfates is shown. (B) Schematic of the pentameric GABAA-gated ion channel and sites for binding of small molecules including the anesthetics propofol, etomidate, and desflurane. Adapted from Lovinger (2008). Cell  , 10-13DOI: ( /j.cell ) Copyright © 2018 Elsevier Inc. Terms and Conditions

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