1. The Building Blocks of Homocystinuria and Homocysteinemia Management

3. Homocysteine

4. Hcy Metabolism Cycle

5. Hyperhomocysteinemia

6. cblC Disease

7. Patient Case 1

8. Patient Case 1 Diagnosis and Treatment

9. Patient Case 1 Follow-up

10. Manifestations of CblC Disease

11. CblC Disease Diagnostic Testing

12. CblC Disease Brain Imaging Findings

13. CblC Disease Treatment

14. CblC Disease Acute Management

15. Long-Term Follow-Up and Surveillance

16. Patient Case 2

17. Patient Case 2 (cont)

18. Homocystinuria Clinical Features

19. Patient Case 2 Laboratory Findings

20. Pyridoxine Responsiveness

21. Assessing Pyridoxine Responsiveness Pyridoxine Challenge

22. Patient Case 2 (cont)

23. Homocystinuria Lab Studies

24. Free Hcy

25. Monitoring and Surveillance for CBS

26. CBS Specific Monitoring

27. Homocystinuria Diet and Medications

28. Homocystinuria Outcomes

29. Homocystinuria Brain Imaging Findings

30. Special Recommendations

31. Concluding Remarks

32. Abbreviations