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Management of Gram-Positive Coccal Bacteremia and Hemodialysis

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Presentation on theme: "Management of Gram-Positive Coccal Bacteremia and Hemodialysis"— Presentation transcript:

1 Management of Gram-Positive Coccal Bacteremia and Hemodialysis
Lynn N. Fitzgibbons, MD, Darcy L. Puls, MD, Kimberly Mackay, PharmD, Graeme N. Forrest, MBBS  American Journal of Kidney Diseases  Volume 57, Issue 4, Pages (April 2011) DOI: /j.ajkd Copyright © Terms and Conditions

2 Figure 1 Electron micrographs of Staphylococcus aureus magnified 348,000 times. (Left) Methicillin-resistant S aureus from Georgia shows a normal cell wall without increased extracellular material; (right) glycopeptide (vancomycin)-intermediate S aureus from Michigan (hemodialysis patient) in which there is increased extracellular material. Panels reproduced from Smith et al34 with permission of the Massachusetts Medical Society. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © Terms and Conditions

3 Figure 2 Scanning electron micrograph of Staphylococcus epidermidis biofilm on foreign material. Reproduced from Zimmerli et al82 with permission of the Massachusetts Medical Society. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © Terms and Conditions

4 Figure 3 Flow diagram for managing Gram-positive cocci in hemodialysis (HD) patients with a central venous catheter (CVC). *Consider transesophageal echocardiography in HD patients with these infections within 5-7 days when possible; should be performed if bacteremia persists longer than 72 hours. Abbreviations: PCR, polymerase chain reaction; PNA FISH, peptide nucleic acid fluorescent in-situ hybridization; MIC, minimum inhibitory concentration; VRE, vancomycin-resistant enterrococci. Source: Mermel et al.9 American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © Terms and Conditions


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