1. A simple asthma prediction tool for preschool children with wheeze or cough 
Anina M. Pescatore, MSc, Cristian M. Dogaru, MD, PhD, Lutz Duembgen, PhD, MSc, Michael Silverman, MD, Erol A. Gaillard, MD, Ben D. Spycher, PhD, Claudia E. Kuehni, MD, MSc 
Journal of Allergy and Clinical Immunology 
Volume 133, Issue 1, Pages e13 (January 2014)
DOI: /j.jaci
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Wheeze, cough, and health care visits in 1- to 3-year-old-children. The illustration shows a proportional Venn diagram for children aged 1 to 3 years, showing frequency of health care visits caused by wheeze or cough, current wheeze, and chronic cough (cough without colds or cough at night). The gray area represents our study population.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Calibration plot of the main model (assessed in leave-one-out cross-validation). Children are grouped into deciles of their predicted probability. The average predicted probability for later asthma among children within each decile is plotted against the actual observed frequency (prevalence) of asthma in that group. As a visual aid, a smoothing technique (locally weighted polynomial regression) was applied to these data. The straight line represents perfect calibration.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
Asthma prediction tool. For any 1- to 3-year-old child seeking health care because of wheeze or cough, the applicable predictors are summed to a total score in the upper part of the figure. The estimated probability of having asthma 5 years later is given below for different total scores.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Fig 4
Receiver operating characteristic curves for the main asthma prediction model and the prediction tool. The dots represent the sensitivity and specificity for different cutoff values of the prediction tool.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6. Fig E1
Original questions used to define inclusion criteria at baseline.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

7. Fig E2 Original questions used to assess outcome at follow-up.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

8. Fig E3 Original questions used as potential predictive factors.
Journal of Allergy and Clinical Immunology  , e13DOI: ( /j.jaci )
Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions